It is clear that the term “white matter disorders” comprises many different disorders which all have different consequences for brain function. For instance, loss of myelin is worse for brain function than increase of water content or formation of scar tissue between nerve fibers. It is therefore also clear that the resulting handicap for the child with a white matter disorder is highly variable, depending on what is happening at brain tissue level.
“White matter disorders” have a bad name. The first thought is usually that the disease is progressive and that the affected child is going to have an increasing neurological handicap and may die. This is true for some disorders, but by no means for all. Some disorders are progressive whereas others are not. It all depends on the cause of the white matter disease.
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The side effects of taking statins include muscle pain and damage, liver damage, digestive problems, rash or flushing, increased blood sugar, type 2 diabetes and neurological side effects, such as memory loss or confusion, according to Mayo Clinic. Muscle pain is the most common side effect. The risk of developing statin side effects can be reduced by limiting alcohol intake and avoiding multiple cholesterol-lowering medications. People with kidney disease, liver disease, or type 1 or 2 diabetes run a greater risk of developing statin side effects. Being female, older than 65 or having a small body frame are also risk factors, states Mayo Clinic.
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Common side effects of a cortisone injection include elevated blood sugar and facial flushing, according to About.com. Other potential side effects include pain, infection, changes in the skin’s pigment, loss of fatty tissue and tendon rupture.
Facial flushing and elevated blood sugar are considered systematic side effects, which means the side effects affect the entire body rather than just the injection site, states About.com. Elevated blood sugar is a side effect that often occurs in those with diabetes, and it is important that those who have diabetes monitor blood sugar levels following a cortisone injection. Facial flushing is seen in about 15 percent of all patients and occurs more commonly in women than men.
Local side effects occur around the site of the injection and are rare, explains About.com. Of these pain is one of the more common ones and sometimes lasts for 24 to 48 hours. For people who have dark complexions, cortisone sometimes causes the skin to lighten. This is a cosmetic change with no other harm associated.
High doses of cortisone have some potentially detrimental effects on tissues of the body, claims About.com. When the cortisone is injected into fatty areas, a condition called fat atrophy sometimes occurs. This condition causes the loss of fatty tissue, which lead to dimpled skin or thinning of fat in some cases.
The side effects of cortisone are Doses of 350 milligrams of magnesium are safe for most adults and generally do not have noticeable side effects, states WebMD. It is best to take magnesium supplements with meals; taking magnesium on an empty stomach may lead to diarrhea. Larger doses of magnesium can lead to abnormal blood pressure or heart rate, slowed breathing, coma and death. Symptoms of an overdose, rare in people with a normally functioning kidney, include blurred or double vision, dizziness or fainting, drowsiness, increased or decreased urination, a slow heartbeat, and trouble breathing, according to Mayo Clinic.
Pregnant or breastfeeding women can likely take magnesium without experiencing any ill effects, but they should check with their doctors before taking it, notes WebMD. Magnesium can affect blood clotting capabilities, so those with bleeding disorders should use it with caution. Magnesium is contraindicated for those with heart block or kidney problems. Dizziness or fainting, flushing, irritation or pain at the injection site, muscle paralysis, and trouble breathing are symptoms that should be reported to a doctor, warns Mayo Clinic. Some side effects are not serious, however, and some dissipate as the body acclimates to the magnesium.